Used to run everything on ESXi until Hock Tan bought VMware. Had a full VMware stack in my homelab minus VSAN and NSX. Horizon, vCenter, etc.
Today I'm on PVE. It's in some ways better, and in some ways worse. I can live with it. I like that it's foundation is just plain Debian, and that the underlying management plane design is so simple. They really took the most pragmatic approach with most things i.e migration and replication uses key-based SSH. I don't like the lack of polish in the GUI and sometimes extremely limited options for storage migration, but performance is good and the price is right!
Running:
Nextcloud
AD domain with 2 servers
IPA domain with 2 servers
HomeAssistant
TrueNAS Core
Some misc VMs for providing network file services for vintage computers
A SIP proxy for my Nortel BCM
PiHole cluster with 2 servers, replication, and keepalived
A Debian 12 VDI box for doing Linux script dev
WikiJS
SearxNG