I’m not sure if they are related, but last night one of my system was unresponsive for a couple of (!!) hours.
CPU usage was around 10 - 30%, memory usage was around 50%, but Disk 0 was a solid 100% for a couple of hours. 🙁
Maxed out Disk 0 would’ve been normal with a near 100% memory and high CPU, but they were both reasonably low, so I have no idea what was happening.
"Disk 0: is right under “Memory” and I’ve never seen it maxed out so long w/o at least maxed out memory – the situation was so bad that even Task Manager wasn’t working right, but since I’ve had an unsaved document, I couldn’t pull the plug.

This is showing a perfectly normal state